This category of drugs is often frightening due to the risk of miscarriage. We take inventory of the bottom of a very widespread therapy.
Seniors are the main customers
Authentic. Used to oppose the formation of clots in the veins, blood vessels, and also the heart, they’re prescribed each year to several million patients in France, mostly seniors. They act on coagulation variables and therefore differ from what are known as antiaggregants (such as aspirin, for example), which merely act on platelets.
We have to take them
True and False. Wearers of particular cardiac prostheses but also patients with atrial fibrillation(regular cardiac arrhythmia which encourages the formation of clots from the heart and exposes stroke) can also be prescribed. In the acute phase, after an event, they’re required to break up a clot currently existing (in the event of phlebitis, as an instance ). Then, a long-term remedy – in oral form this time – is set up to stop the formation or reformation of a clot. This can last from a few months (such as phlebitis) to a couple of years (after a pulmonary embolism). Anticoagulants may also be recommended preventively, chiefly in patients identified at high risk for phlebitis or who suffer from atrial fibrillation. This is then treated daily. This also often explains poor compliance. It is projected that three decades after beginning treatment, 30 percent of patients choose their anticoagulant poorly or in any way. To assist patients and prevent these treatment fractures, there are a number of tools such as the mobile application AVK laptop.
These are very restrictive medications
It all depends on the form of anticoagulants we’re talking about. The earliest (they have been around since 1940), anti-vitamin K (AVK), in actuality, have a major drawback despite their efficacy: the responsibility of permanent monitoring of the individual, through a coagulation assessment each month. Additionally, the dosage varies from 1 person to another and in an unpredictable manner as time passes, which demands permanent adjustments. Ultimately, AVKs are extremely sensitive to this concomitant intake of different medications but also to specific kinds of meals (abundant in vitamin K). Simply speaking, they are binding.
New molecules are revolutionizing care
Authentic. Direct oral anticoagulants (DOACs), that arrived in the late 2000s, are easier to handle since they require little hands. They have a decreased risk of interactions with drugs apart from VKA and not one with food. These new production molecules are now prescribed as first-line treatment. Main contraindications: patients with poor renal function (since they remove them poorly) and those who have coronary artery prostheses.
There’s a real risk of bleeding
True. Regularly benign (gums, nose, digestive mucous membranes, etc.), they become serious if they influence an important organ, like the brain. But recent studies have revealed that the oral anticoagulants are safer to work with than VKA (less chance of intracerebral bleeding) having an equal benefit (the famed antithrombotic activity ), that explains why they are preferred. today.
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